Invited Plenary Lecture - VI. Conference on biological psychiatry
June 6, 2017
A Journey into the Molecular Depth of the Brain
Robert Mistrik
HighChem, Bratislava, Slovakia

Keynote Lecture - EUROTOX 2017, 53rd Congress of the European Societies of Toxicology, Bratislava, Slovakia
September 10-13, 2017
The growing analytical fallacy: The majority of small molecules on earth remains unidentified, while hundreds of molecules have been reported in space
Robert Mistrik
HighChem, Bratislava, Slovakia

Talk - 65th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, USA
June 4-8, 2017
Paradigm Change in de novo Identification of Small Molecules: Giant Spectral Trees
Tim J. Stratton1, Jakub Mezey2, Alena Bednarikova2, Jana Semanova2, Robert Mistrik2
1Thermo Fisher Scientifric, San Jose, Ca, USA; 2HighChem, Bratislava, Slovakia

Poster Presentation - 65th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, USA
June 4-8, 2017
Comprehensive Statistical Analysis of the Largest High Resolution Small Molecule ESI/APCI Library as Condition for Confident Compound ID
Michal Raab, Juraj Lutisan, Milos Suchy, Robert Mistrik
HighChem, Bratislava, Slovakia

Publication - Nature Biotechnology
SPLASH, a hashed identifier for mass spectra
Gert Wohlgemuth1, Sajjan S Mehta1, Ramon F Mejia2, Steffen Neumann3, Diego Pedrosa1, Tomáš Pluskal4, Emma L Schymanski5, Egon L Willighagen6, Michael Wilson7, David S Wishart7, Masanori Arita2,8, Pieter C Dorrestein9,10, Nuno Bandeira9,11,12, Mingxun Wang11,12, Tobias Schulze13, Reza M Salek14, Christoph Steinbeck14, Venkata Chandrasekhar Nainala15, Robert Mistrik15, Takaaki Nishioka16 and Oliver Fiehn1,17
1West Coast Metabolomics Center and Genome Center University of California Davis, Davis, California, USA. 2RIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan. 3Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany. 4Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts, USA. 5Eawag: Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland. 6Department of Bioinformatics-BiGCaT, Maastricht University, Maastricht, The Netherlands. 7Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada. 8National Institute of Genetics, Mishima, Shizuoka, Japan. 9Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, California, USA. 10Departments of Pharmacology and Pediatrics, School of Medicine, UC San Diego, La Jolla, California, USA. 11Computer Science and Engineering, UC San Diego, La Jolla, California, USA. 12Center for Computational Mass Spectrometry, UC San Diego, La Jolla, California, USA. 13Department of Effect-Directed Analysis, UFZ Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany. 14European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK. 15HighChem Ltd., Bratislava, Slovakia. 16Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Kyoto, Japan.

Keynote Lecture - 37th British Mass Spectrometry Society annual meeting, Eastbourne, UK
September 13-15, 2016
mzCloud: A comprehensively annotated LC/MSn database for the identification of unknowns
Juraj Lutisan, Michal Raab; Milos Suchy; Jakub Mezey; Martin Mandak, and Robert Mistrik
HighChem, Bratislava, Slovakia

Talk - 12th Annual Conference of the Metabolomics Society, Dublin, Ireland
June 27-30, 2016
mzCloud: An online substructural database of spectral trees for the identification of metabolites
Robert Mistrik
HighChem, Bratislava, Slovakia

Publication - International Journal of Molecular Sciences
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics
Manoj Ghaste1, Robert Mistrik2 and Vladimir Shulaev1
1Department of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 76203, USA; 2HighChem, Bratislava 81104, Slovakia

Publication - Food Chemistry
Elimination of polycyclic aromatic hydrocarbons from smoked sausages by migration into polyethylene packaging Jana Semanová1, Božena Skláršová2, Peter Šimon3, Peter Šimko 2
1HighChem Ltd., Leškova 11, 811 04 Bratislava, Slovak Republic; 2Institute of Food Science and Nutrition, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic; 3Institute of Physical Chemistry and Chemical Physics, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic

Talk and Poster Presentation - 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, USA
June 5-9, 2016
Prediction of CID/HCD Spectra by First-Principle Molecular Dynamics for Aimed Routine Compound ID
Michal Raab and Robert Mistrik
HighChem, Bratislava, Slovakia

Poster Presentation - 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, USA
June 5-9, 2016
mzCloud, a First Quantum Chemically Annotated Mass Spectral Database
Michal Raab1, Chongle Pan2, Milos Suchy1, Martin Mandak1, Juraj Lutisan1, Jakub Mezey1, Robert Mistrik1
1HighChem, Bratislava, Slovakia; 2Oak Ridge National Laboratory, Oak Ridge, TN, USA

Workshop - 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, USA
June 5-9, 2016
Metabolomics: Emerging Technologies for Continued Innovation
mzCloud; Robert Mistrik
HighChem, Bratislava, Slovakia

Publication - Metabolites
The Time Is Right to Focus on Model Organism Metabolomes
Arthur S. Edison1, Robert D. Hall2, Christophe Junot3, Peter D. Karp4, Irwin J. Kurland5, Robert Mistrik6, Laura K. Reed7, Kazuki Saito8, Reza M. Salek9, Christoph Steinbeck9, Lloyd W. Sumner10 and Mark R. Viant11,*
2016, 6(1), 8; doi:10.3390/metabo6010008
1Departments of Genetics and Biochemistry, Complex Carbohydrate Research Center and Institute of Bioinformatics, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA; 2Wageningen University & Research Centre, PO Box 16, 6700AA Wageningen, The Netherlands; 3CEA, iBiTec-S, Service de Pharmacologie et d’Immunoanalyse, Laboratoire d’Etude du Métabolisme des Médicaments, MetaboHUB-Paris, CEA Saclay, Building 136, 91191 Gif-sur-Yvette cedex, France; 4Bioinformatics Research Group, SRI International, 333 Ravenswood Avenue AE206, Menlo Park, CA 94025, USA; 5Albert Einstein College of Medicine, 1301 Morris Park Avenue, Bronx, NY 10461, USA; 6HighChem LLC, Leskova 11, 81105 Bratislava, Slovakia; 7Department of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35487, USA;8RIKEN Center for Sustainable Resource Science, Yokohama 230-0045; Chiba University, Chiba 260-8675, Japan; 9European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK; 10University of Missouri, Department of Biochemistry, Columbia, MO 65211, USA; 11School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK

Talk - SULSA Scottish Metabolomics Network Inaugural Meeting, University of Edinburgh, UK
November 30-December 1, 2015
Applying mzCloud in known and unknown metabolite ID applied to metabolomics
Robert Mistrik
HighChem, Bratislava, Slovakia

Invited Lecture - Extractables & Leachables Europe 2015, London, UK
November 10-12, 2015
Development and Utilization of Cloud Based Libraries for Unknown Contaminant Identification
Robert Mistrik
HighChem, Bratislava, Slovakia

Invited Plenary Lecture - 33rd meeting of the Swiss Group for Mass Spectrometry, Beatenberg, Switzerland
October 29-30, 2015
The great paradox of the 21st century: We are unable to identify 70-90% of small molecules in biological samples and rivers on Earth, while humans have endeavored to analyze the soil on Mars, the atmosphere on Jupiter and the sea on Titan.
Robert Mistrik
HighChem, Bratislava, Slovakia

Workshop - MSACL 2015 EU, Salzburg, Austria
September 8-11, 2015
Identifying unknown unknowns with high resolution accurate mass MS in toxicology
Robert Mistrik
HighChem, Bratislava, Slovakia

Talk - 11th International Conference of the Metabolomics Society, San Francisco, USA
June 29-July 2, 2015
Metabolomics meets quantum chemistry: a novel strategy towards reliable computer-assisted structure elucidation of metabolites
Robert Mistrik, Michal Raab, Juraj Lutisan
HighChem, Bratislava, Slovakia

Poster Presentation - 63rd ASMS Conference on Mass Spectrometry and Allied Topics, St. Louis, MO, USA
May 31-June 4, 2015
A Comparison of Sequential Fragmentation at High Energies with True MSn Analysis Utilizing Energy Dependent Breakdown Curves
Tim Stratton1, Robert Mistrik2
1Thermo Fisher Scientific, San Jose, CA, USA; 2HighChem, Bratislava, Slovakia

Poster Presentation - 63rd ASMS Conference on Mass Spectrometry and Allied Topics, St. Louis, MO, USA
May 31-June 4, 2015
Advancing Computer-Assisted Structure Elucidation Methods: A Large-Scale Fragment Assignment Project using Heuristic and Molecular Modeling Methods
Michal Raab, Juraj Lutisan, Robert Mistrik
HighChem, Bratislava, Slovakia

Invited Lecture - 4th Conference of Czech Society for Mass Spectrometry, Hradec Kralove, CZ
April 15-17, 2015
Can quantum chemistry save the mass spectrometry?
Robert Mistrik
HighChem, Bratislava, Slovakia

Invited Lecture - CECE 2014, 11th International Interdisciplinary Meeting on Bioanalysis, Brno, CZ
October 20-22, 2014
A light at the end of the tunnel for the comprehensive compound identification in untargeted metabolomics
Robert Mistrik
HighChem, Bratislava, Slovakia

Invited Lecture - 9th Aegean Analytical Chemistry Days, Chios, Greece
September 29 - October 3, 2014
Solving the Identification Bottleneck Using mzCloud, A Novel Database of High Resolution Mass Spectra
Robert Mistrik
HighChem, Bratislava, Slovakia

Talk - Workshop on Non-Target Screening, Dübendorf, Switzerland
September 16-17, 2014
Advanced spectral processing and management
Robert Mistrik
HighChem, Bratislava, Slovakia

Keynote Lecture - International Mass Spectrometry Conference, 2014, Geneva, Switzerland
August 24-29, 2014
Beyond the elemental composition: Computer-assisted identification methods in a high resolution era
Robert Mistrik
HighChem, Bratislava, Slovakia

Poster Presentation - International Mass Spectrometry Conference, 2014, Geneva, Switzerland
August 25, 2014
Autonomous Orbitrap platform for acquisition of MSn spectral trees based on intelligent, real time decision making logic
Robert Mistrik1, Jakub Mezey1, Juraj Lutisan1, Tim Stratton2, Lukas Najdekr2,3
1HighChem, Bratislava, Slovakia; 2Thermo Fisher Scientific, San Jose, CA, USA; 3IMTM, Palacky University, Olomouc, Czech Republic

Talk - CoSMoS 2014, Conference on Small Molecule Science, Williamsburg VA, USA
August 11-13 2014
The mzCloud - Applications of Cloud Computing in Mass Spectrometry
Robert Mistrik
HighChem, Bratislava, Slovakia

Talk - 53rd annual meeting of the Phytochemical Society of North America, Raleigh NC, USA
August 10, 2014
A Novel Cloud Approach to Solving the Identification Bottleneck in the Untargeted Metabolomics
Robert Mistrik
HighChem, Bratislava, Slovakia

Publication - Metabolomics, Volume 10, Issue 3, pp 350-353
June 2014
Metabolite identification: are you sure? And how do your peers gauge your confidence?
Darren J. Creek, Warwick B. Dunn, Oliver Fiehn, Julian L. Griffin, Robert D. Hall, Zhentian Lei, Robert Mistrik, Steffen Neumann, Emma L. Schymanski, Lloyd W. Sumner, Robert Trengove, Jean-Luc Wolfender

Talk - 10th Annual International Conference of the Metabolomics Society, Tsuruoka, Japan
June, 23-26, 2014
An advanced computational and database framework for the compound identification in untargeted metabolomics
Robert Mistrik1, Tim Stratton2, Milos Suchy1, Alena Bednarikova1, Yingying Huang2, Mark Sanders2
1HighChem, Bratislava, Slovakia; 2Thermo Fisher Scientific, San Jose, CA, USA

62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD, USA
June 15-19, 2014
Autonomous Orbitrap platform for acquisition of MSn spectral trees based on intelligent, real time decision making logic
Robert Mistrik1, Jakub Mezey1, Juraj Lutisan1, Tim Stratton2, Lukas Najdekr2,3
1HighChem, Bratislava, Slovakia; 2Thermo Fisher Scientific, San Jose, CA, USA; 3IMTM, Palacky University, Olomouc, Czech Republic

62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD, USA
June 15-19, 2014
Understanding of fundamental ion behavior leads to routine substructure identification: A mechanistic study on precursor ions
Michal Raab, Robert Mistrik
HighChem, Bratislava, Slovakia

62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD, USA
June 15-19, 2014
Addressing identification ambiguity in untargeted metabolomics by processing raw spectra into a high quality reference data
Robert Mistrik1, Juraj Lutisan1, Yingying Huang2, Mark Sanders2, Eric Genin3
1HighChem, Bratislava, Slovakia; 2Thermo Fisher Scientific, San Jose, CA, USA; 3Thermo Fisher Scientific, Villebon sur Yvette, France

Talk - 8e Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique, Lyon, France
May 19-21, 2014
mzCloud and Mass Frontier: A key conceptual shift to understand “who’s who” in untargeted metabolomics
Robert Mistrik
HighChem, Bratislava, Slovakia

Publication - Bioinformatics
HAMMER: automated operation of Mass Frontier to construct in silico mass spectral fragmentation libraries.
Jiarui Zhou1, Ralf J. M. Weber2, J. William Allwood2, Robert Mistrik3, Zexuan Zhu4, Zhen Ji4, Siping Chen5, Warwick B. Dunn2, Shan He6 and Mark R. Viant2
1College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China, 2School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK, 3HighChem, Ltd., Leskova 11, 81104 Bratislava, Slovakia, 4Shenzhen City Key Laboratory of Embedded System Design, College of Computer Science and Software Engineering, 5School of Medicine, Shenzhen University, Shenzhen 518060, China and 6School of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK

Poster Presentation - 9th International Conference of the Metabolomics Society, Glasgow, Scotland
July 1-4, 2013
mzCloud: A key conceptual shift to understand “who’s who” in untargeted metabolomics
Robert Mistrik1, Juraj Lutisan1, Yingying Huang2, Milos Suchy1, Junhua Wang2, Michal Raab1
1HighChem, Bratislava, Slovakia; 2Thermo Fisher Scientific, San Jose, CA, USA

Oral Presentation – 61st ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, USA
June 13, 2013
Untargeted metabolomics: From statistical objects to the efficient identification of “known unknowns”
Robert Mistrik, Juraj Lutisan, HighChem, Slovakia

Lecture - EMBO Practical Course on Metabolomics Bioinformatics for life Scientists, Cambridge, UK
March 1, 2013
The m/z Cloud
Robert Mistrik, HighChem, Slovakia

Publication - Rapid Communications in Mass Spectrometry
Fragmentation trees for the structural characterisation of metabolites.
Kasper, Piotr T.1, Miguel Rojas‐Chertó1, Robert Mistrik2, Theo Reijmers1, Thomas Hankemeier1, and Rob J. Vreeken1.
DOI: 10.1002/rcm.6340
1Netherlands Metabolomics Centre, Leiden, The Netherlands; 2HighChem Ltd., Bratislava, Slovakia

Keynote lecture - 29th Montreux Symposium on LC/MS, Montreux, Switzerland
November 7, 2012
Identification of Unknowns using Mass Spectral Library Cloud
Robert Mistrik, HighChem, Slovakia

Workshop - Metabomeeting - Manchester, UK
September 25, 2012
m/z Cloud - Novel Spectral Library for Metabolite Identification
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 8th International Conference of the Metabolomics Society, Washington, DC, USA
June 25-28, 2012
m/z Cloud – A New Type of Mass Spectral Library for the Identification of Unknowns even if the Unknown Compound is not Present in the Library
Robert Mistrik, Juraj Lutisan: HighChem, Slovakia
Mark Sanders; Yingying Huang; Rose Herbold; Tim Stratton: Thermo Fisher Scientific, San Jose, CA, USA

Poster Presentation - 60th ASMS Conference on Mass Spectrometry and Allied Topics, Vancouver, Canada
May 22, 2012
A Novel Type of Spectral Library for the Identification of "Unknown Unknowns"
Robert Mistrik, Juraj Lutisan, HighChem, Slovakia

Oral Presentation - A Perspective on the Processing and Analysis of Mass Spectrometry Data, Manchester, UK
May 2, 2012
Utilizing molecular evolutionary patterns for mass spectra interpretation
Robert Mistrik, HighChem, Slovakia

Lecture - EDA-EMERGE Kick Off Meeting, Stockholm, Sweden
November 21, 2011
Spectral Trees: A modern Way of Building Spectral Libraries
Robert Mistrik, HighChem, Slovakia

Metabolomics Seminar – Stanford University, Stanford, USA
October 7, 2011
Utilizing Molecular Evolutionary Patterns for Mass Spectra Interpretation
Robert Mistrik, HighChem, Slovakia

Metabolomics Seminar - Lawrence Berkeley National Laboratory, Berkley, USA
October 6, 2011
Utilizing Molecular Evolutionary Patterns for Mass Spectra Interpretation
Robert Mistrik, HighChem, Slovakia

Keynote Lecture - 27th Asilomar Conference on Mass Spectrometry, San Jose, USA
October 1, 2011
Substructure Paths for Compound Identification
Robert Mistrik, HighChem, Slovakia

Oral Presentation - 59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, USA
June 9, 2011
A Third Generation Spectra Correlation Algorithm and Its Implementation in Library Search, Identification of Unknowns and Metabolite ID
Robert Mistrik, Juraj Lutisan, HighChem, Slovakia

Thermo User Meeting, Frankfurt, Germany
May 3, 2011
Fragment Ion Search (FISh): A Novel Technique for Metabolite Detection and Identification
Robert Mistrik, HighChem, Slovakia

Workshop - 27th Montreux Symposium on LC/MS, Montreux, Switzerland
November 10, 2010
Mass Frontier 7.0: One small step for Mass Frontier, one giant leap for metabolite identification and structural elucidation
Robert Mistrik, HighChem, Slovakia

Oral Presentation - TransCon 2010- Environmental Transformation of Organic Compounds, Ascona, Switzerland
September 13, 2010
Metabolite Detection and Identification
Robert Mistrik, HighChem, Slovakia

Invited Plenary Lecture – TOXCON 2010, Stará Lesná, Slovakia
September 9, 2010
Determination of Ion structures in Structurally Related compounds using Precursor Ion Fingerprinting
Robert Mistrik, HighChem, Slovakia

Oral Presentation - 58th ASMS Conference on Mass Spectrometry and Allied Topics, Salt Lake City, UT, USA
May 27, 2010
Metabolite Detection and Identification Using Fragment Ion Search in Conjunction with Automated Fragment Prediction
Juraj Lutisan; Robert Mistrik, Milos Suchy, HighChem, Slovakia
Yingying Huang, Thermo Fisher Scientific, San Jose, CA, USA
Alexej Nikiforov, University of Vienna, Vienna, Austria

Workshop - LC/MS Andwenderforum 2010, Marburg, Germany
May 4, 2010
Computer Assisted Structure Elucidation Using Mass Frontier Software
Robert Mistrik, HighChem, Slovakia

Scientific Seminar at Boehringer Ingelheim, ThermoFischer Scientific, Dreieich, Germany
November 3, 2009
From MSMS and Manual Spectra Interpretation to Computer Assisted Structure Elucidation
Robert Mistrik, HighChem, Slovakia

Odborný seminár - FCHPT STU, Bratislava, Slovakia
Október 21,2009
Smerovanie k automatickej štrukturnej analýze malých molekúl pomocou hmotnostnej spektrometrie.
Robert Mistrik, HighChem, Slovakia

Lecture - MetaCancer Plenary Meeting, Cambridge, UK
October 2, 2009
Structure Elucidation of Small Molecules in Biomarker Research Using Mass Spectrometry
Robert Mistrik, HighChem, Slovakia

Oral Presentation - Conference on Small Molecule Science – COSMOS, Boston, MA, USA
August 4, 2009
Structural Analysis of Small Molecules Using Precursor Ion Fingerprintign (PIF)
Robert Mistrik, HighChem, Slovakia

Poster Presentation - ASMS 57th Conference, Philadelphia, Pensylvania, USA
May 31 - June 4, 2009
A New and Universal Product Ion Nomenclature for Low- and High-Energy CID of Sodiated Glycerophospholipid Precursor Ions
Ernst Pittenauer; Guenter Allmaier, Vienna University of Technology, Vienna , Austria
Robert Mistrik, HighChem, Slovakia

Lecture - MetaCancer Plenary Meeting, Davis, CA, USA
May 27, 2009
Identification of Novel Disease Biomarkers by Mass Spectrometry
Robert Mistrik, HighChem, Slovakia

Publication - Journal of the American Society for Mass Spectrometry
March 2009
Determination of Ion Structures in Structurally Related Compounds Using Precursor Ion Fingerprinting
Michelle T. Sheldon1, Robert Mistrik2 and Timothy R. Croley1
1Commonwealth of Virginia, Department of General Services, Division of Consolidated Laboratory Services, 600 N 5th Street, Richmond VA 23219, United States 2HighChem, Ltd., Cajakova 18, 81105 Bratislava, Slovakia

Invited Lecture - Metabolomics Society 4th Annual Conference, Boston, MA, USA
September 3-6, 2008
Integrated Approach for Structural Analysis of Endogenous Metabolites
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 56th ASMS Conference on Mass Spectrometry, Denver, CO, USA
June 1 - 5, 2008
Determination of the Ion Structures of Isomers Using Precursor Ion Fingerprinting
Michelle Sheldon 3; Robert Mistrik2; Timothy R. Croley1
1Commonwealth of Virginia, Richmond, VA; 2HighChem, Bratislava, Slovakia; 3Div of Consolidated Lab, Richmond, VA

Poster Presentation - 56th ASMS Conference on Mass Spectrometry, Denver, CO, USA
June 1 - 5, 2008
PIF: Precursor Ion Fingerprinting–Searching for Genesis Fragments using LC-MSn
Julie A. Horner1; Mark Sanders1;Robert Mistrik2
1Thermo Fisher Scientific, San Jose, CA; 2HighChem, Bratislava, Slovakia

Oral presentation - 1st METAcancer Meeting, Berlin, Germany
May 19-20, 2008
Strategy for identification of new breast cancer biomarkers using LC-MS and Precursor Ion fingerprinting (PIF)
Robert Mistrik, Juraj Lutisan, Milos Suchy , HighChem, Slovakia

Oral Presentation - Computer Application Workshop at 55th ASMS Conference, Indianapolis, IN, USA
June 3 - 7, 2007
Efficient processing of spectral, structural and chromatographic data acquired by MSn and high resolution techniques
Robert Mistrik , HighChem, Slovakia

Poster Presentation - 55th ASMS Conference, Indianapolis, IN, USA
June 3 - 7, 2007
Determination of Ion Structures in Structurally Related Compounds Using Precursor Ion Fingerprinting
Michelle Sheldon 3; Robert Mistrik2; Timothy R. Croley1
1Commonwealth of Virginia, Richmond, VA; 2HighChem, Bratislava, Slovakia; 3Div of Consolidated Lab, Richmond, VA

Poster Presentation - 55th ASMS Conference, Indianapolis, IN, USA
June 3 - 7, 2007
Automated Identification of Unknown Compounds Employing Nanoelectrospray LC/MS Coupled with Infusion MSn Employing the Concept of Precursor Ion Fingerprinting
1Timothy R Croley, 1Frederic L. Ciner, 1Michelle Sheldon, 1Robert A Everley, 2Gary Schultz, 2Ellen Pace, 3Robert Mistrik, 2Jack Henion
1Commonwealth of Virginia, Richmond, VA; 2Advion Biosciences, Ithaca, NY; 3HighChem, Bratislava, Slovakia

Patent - United States Patent, No.: US 7,197,402 B2
March 27, 2007
Determination of Molecular Structures Using Tandem Mass Spectrometry
Robert Mistrik, HighChem, Slovakia

Key Note Lecture - MassSpec-Forum, Vienna, Austria
February 20 - 21, 2007
A „Cool“ Outlook on „Uncool“ Fragmentation Processes
Robert Mistrik, HighChem, Slovakia

Oral Presentation - CECE 2006, Brno, Czech Republic
November 13 -14, 2006
Mass spectrometric strategy for structural mapping of endogenous metabolites
Robert Mistrik, HighChem, Slovakia

Oral Presentation - CDC Level 1 Meeting, Minnesota, MI, USA
September 26 - 28 2006
Determination of Molecular Structures by Precursor Ion Fingerprinting
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 17th International Mass Spectrometry Conference, Prague, Czech Republic
August 27 - September 1, 2006
Primary (Sub-) Structure Proposals for General Unknowns with EI Spectra not Available in LR MS-libraries Using HR MS-Data and HR Fragmentation Library
1Alexej Nikiforov, 2Winfried Wagner-Redeker, 3Juraj Lutisan, 3Milos Suchy and 3Robert Mistrik
1University of Vienna, Vienna Austria, 2Spectronex AG, 2Basel, Switzerland, 3HighChem, Bratislava, Slovakia

Poster Presentation - 17th International Mass Spectrometry Conference, Prague, Czech Republic
August 27 - September 1, 2006
Bioinformatics for the Human Metabolome Project: Integrated Approach for Structural Mapping of Endogenous Metabolites
Robert Mistrik, Juraj Lutisan and Milos Suchy, HighChem, Bratislava, Slovakia

Publication - Journal of Mass Spectrometry
2006; 41: 421-447
Comparison of CID spectra of singly charged polypeptide antibiotic precursor ions by positive-ion vacuum MALDI IT/RTOF and TOF/RTOF, AP-MALDI-IT and ESI-ITmass spectrometry
Ernst Pittenauer1, Martin Zehl1, Omar Belgacem2, Emmanuel Raptakis2, Robert Mistrik3 and Gunter Allmaier1
1Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna, Austria; 2Shimadzu Biotech Kratos Analytical, Manchester, UK; 3HighChem, Bratislava, Slovakia

Oral Presentation - 54th ASMS Conference, Seattle, WA, USA
May 28 - June 1, 2006
Integrated Approach for Structural Profiling of Endogenous Metabolites
Robert Mistrik, Juraj Lutisan and Milos Suchy, HighChem, Slovakia

Poster Presentation - 53rd ASMS Conference, San Antonio, TX, USA
June 5-9, 2005
Comparative Fragmentation Study of Polypeptide Antibiotics by Low Energy-CID (ESI- and MALDI-Ion Trap) Multistage MS and High Energy-CID (MALDI-rTOF) MS/MS
Ernst Pittenauer, Martin Zehl, Omar Belgacem, Robert Mistrik and Guenter Allmaier

Oral Presentation - 17th Massenspektrometrische Diskussionsveranstaltung, Vienna, Austria
February 14 - 15, 2005
Automated Determination of Molecular Structures by Precursor Ion Fingerprinting (PIF)
Robert Mistrik1, Juraj Lutisan1, Milos Suchy1 and Ernst Pittenauer2
1HighChem, Bratislava, Slovakia; 2Vienna University of Technology, Vienna, Austria

Oral Presentation - 21st LC/MS Montreux Symposium, Switzerland
November 10-12, 2004
Harnessing the Complexity of LC-MSn Data
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 7th Annual Symposium on Chemical and Pharmaceutical Structure Analysis, Princeton, NJ, USA
October 19 - 21, 2004
Mappa Humanus: Mapping and Spectral Characterization of the Human Metabolome
Robert Mistrik1, Juraj Lutisan1, Milos Suchy1, Ernst Pittenauer2 and Guenter Allmaier2
1HighChem, Bratislava, Slovakia; 2Vienna University of Technology, Vienna, Austria

Oral Presentation - 20th Asilomar Conference on Mass Spectrometry, Pacific Grove, CA
October 15 – 18, 2004
Mapping Human Metabolome: Is this a software problem?
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 52nd ASMS Conference, Nashville, TN, USA
May 26, 2004
Comprehensive Database of Mechanisms of Peptide Fragmentation - A Key Step towards Confident Identification of Proteins
Robert Mistrik, HighChem, Slovakia.

Poster Presentation - 52nd ASMS Conference, Nashville, TN, USA
May 26, 2004
Evaluation of ESI-MSn Ion Trap and MALDI-MSn Ion Trap/Reflectron TOF Mass Spectra (n=1-3) for Incorporation into a Searchable Database
Ernst Pittenauer1; Martin Zehl1; Robert Mistrik2 and Günter Allmaier1
1Vienna University of Technology, Vienna, Austria; 2HighChem, Bratislava, Slovakia

Publication - Naturwissenschaften
2004 May;91(5):209-14. Epub 2004 Mar 19
A butterfly's chemical key to various ant forts: intersection-odour or aggregate-odour multi-host mimicry?
Birgit C. Schlick-Steiner; Florian M. Steiner; Helmut Höttinger; Alexej Nikiforov; Robert Mistrik; Christa Schafellner; Peter Baier and Erhard Christian

Oral Presentation - 9th Annual Meeting of European Network of the Official Medicines Control Laboratories (OMCLs), Langen, Germany
May 14, 2004
An ESI-MSn Library for Ion Traps: Comparable to Wiley/NIST/Maurer-Pfleger Library?
Ernst Pittenauer, Günter Allmaier and Robert Mistrik

Oral Presentation - XV. Massenspektrometrischen Diskussionsveranstaltung, Vienna, Austria
February 18, 2004
A new MSn-based concept with software implementation
Robert Mistrik; Alexej Nikiforov; Ernst Pittenauer; Milos Suchy and Juraj Lutisan

Poster Presentation - 16th IMSC Conference, Edinburgh, UK
September 4, 2003
A New Concept for the Interpretation of Mass Spectra Based on a Combination of a Fragmentation Mechanism Database and a Computer Expert System
Robert Mistrik, HighChem, Ltd.

Publication - Journal of Mass Spectrometry
2003; 38: 924–930
Electron ionization mass spectrometric study of monomeric models of O-polysaccharides of Vibrio cholerae O:1, serotypes Ogawa and Inaba
Vladimir Kovacik; Vladimir Patoprsty; Pentti Oksman; Robert Mistrik and Pavol Kovac

Mass Spectral Database Initiative Meeting - ASMS 2003 Montreal, Canada
June 10, 2003
Power Point Presentation
Speach of Robert Mistrik, HighChem, Ltd.

Poster Presentation - 51nd ASMS Conference, Montreal, Canada
June 11, 2003
A New MSn Database Concept With Sample Library
Robert Mistrik; Alexej Nikiforov; Ernst Pittenauer; Milos Suchy and Juraj Lutisan

Oral Presentation - XIV. Massenspektrometrischen Diskussionsveranstaltung, Vienna, Austria
February 19, 2003
Data Mining in der Massenspektrometrie: Target Analyse in LC/MS/MS-Datensätzen unter Verwendung von MS/MS-Datensätzen und SOM
Alexej Nikiforov, Klaus Kaiser, Winfried Wagner-Redeker and Robert Mistrik

Publication - Journal of Chemical Ecology
28 (12): 2569-2584, December 2002
Cuticular Hydrocarbons of Tetramorium Ants from Central Europe: Analysis of GC-MS Data with Self-Organizing Maps (SOM) and Implications for Systematics
Florian M. Steiner ; Birgit C. Schlick-Steiner; Alexej Nikiforov; Roland Kalb and Robert Mistrik

Oral Presentation - IX. Konferencia Súčasný Stav a Perspektívy Analytickej Chémie v Praxi, Bratislava, Slovakia
September 4, 2002
Moderné Trendy v Interpretacii Hmotnostných Spektier
Robert Mistrik, HighChem, Slovakia

Poster Presentation - 50th ASMS Conference, Orlando, FL, USA
June 3, 2002
Data mining in mass spectrometry using higher dimensions of Self-Organising Maps (SOM 40x40 to 200x200) for identification of unknowns with NIST library
Alexej Nikiforov; Julia E. Wingate and Robert Mistrik

Poster Presentation - 50th ASMS Conference, Orlando, FL, USA
June 3, 2002
The Use of Mass Frontier Software in the Elucidation of Electrospray Tandem Mass Spectrometry Fragmentation of [M+Na]+ Ions of Oligomeric Lipopolysaccharide Models
Vladimir Kovacik; Vladimir Patoprsty; Jozef Caslavsky; Jozef Chmelik; Robert Mistrik and Pavol Kovac

Poster Presentation - The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, LA, USA
March 20, 2002
Profiling of GC and GC-MS Data Sets by PCA and Self-Organizing Maps (SOM) for Correlations of Multiple Data Attributes
Alexej Nikiforov; Barbara Remberg and Robert Mistrik