HighChem Mass Frontier™ 5.0 is a software package for the management, evaluation and interpretation of mass spectra. This software provides a number of useful tools for processing and organizing mass spectral and chromatographic data. Because of the large volume of information a mass spectrometer can produce, management capabilities are essential in mastering your analytical workloads. In contrast to other software systems, Mass Frontier offers many sophisticated features for the efficient interpretation of mass spectra even where an unknown is not contained in your user-contributed or commercially available library. Many of its features are innovative and unique, so you will need to take a few minutes to familiarize yourself with them. In addition, we will try to show you some new ways to review your data and how to use the power of Mass Frontier to interpret mass spectra.